Sometimes a drug is being used for the first time in humans. The treatment may be given to people with different types of cancers. A Phase I trial is mainly a drug safety study and tends to be small, enrolling around 20 patients.
Phase II trials study how well a treatment works for a certain cancer. These trials may include between 25 and people.
Phase III trials compare the new drug or procedure to accepted standard treatment to see which works the best. Phase III trials may look at different doses of the same drug, different drug combinations or different sequences of giving drugs.
In these trials, people are randomized to get either the new treatment or the standard treatment. Phase III trials are large, enrolling hundreds or sometimes even thousands of participants.
While a clinical trial is a good choice for some people, clinical trials have possible benefits and drawbacks. You can always stop participating in the clinical trial at any time. For more information on cancer clinical trials or research studies, ask your medical care provider or call or send an email to winshipcto emory.
Types of Clinical Trials A clinical trial is a form of research that enlists participants to help answer specific questions about new ways to prevent, diagnose, and treat cancer. Clinical trials occur in three phases necessary for FDA approval of a new treatment option:. Both ambulatory and hospitalised patients may be enrolled and randomised.
Patients currently hospitalised for HF, must be off intravenous HF medications for at least 24 before randomisation. Further details regarding inclusion criteria may apply. Exclusion Criteria: 1. Type 1 diabetes mellitus T1D. Stroke or transient ischemic attack TIA within 12 weeks prior to enrolment. Probable alternative or concomitant diagnoses which in the opinion of the investigator could account for the patient's HF symptoms and signs e.
Further exclusion criteria may apply. Purpose: The purpose of this study is to investigate the factors that lead to increased risk or resilience to cardiovascular disease, specifically within African American communities in Atlanta.
The study has three major projects. First, risky and resilient communities in the greater Atlanta area will be determined using publicly-available demographic and hospitalization data.
Next, individuals from these communities will be called and asked to participate in multiple surveys that will further characterize their health, personal beliefs and community characteristics.
Finally, a small group of individuals from these phone calls will participate in further clinical testing to determine their degree of blood vessel disease. Patients with history of angiographically-proven or suspected Coronary Artery Disease age 30 - 80 undergoing a clinically indicated diagnostic heart catheterization are invited to participate in the study.
In addition to standard diagnostic angiography, a wire will be placed inside an unblocked coronary artery to measure blood flow before and after mental stress using standardized mental stress testing scenarios as well as following infusion of intracoronary acetylcholine, adenosine and nitro.
The research protocol cannot be easily changed. For this, you must submit a special application to the authorized governmental body. For more information about available research studies, please contact the research team at: - - For patients For Collaborators Careers.
Patient Contact. What is Informed Consent? How are Clinical Trials Regulated? What is the Clinical Trial Protocol? Study design. Research purpose and significance. Place and time of study. Methodology and procedures that are planned to be used.
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